NAOMInova is a software tool enabling the geometrical and chemical analysis of atoms surrounding a user-defined structure of interest. Based on a user-selected set of protein structures, substructures can be searched and the distribution of partner points can be visualized. Two visualization options are available: the „set“ visualization, i.e. the partner points surrounding the substructure, and the „pocket“ visualization, i.e. the transformation of all partner points surrounding the substructure into a suitable active site of interest. Diverse geometric - distance, angles, resolution - and chemical - atom type, location, amino acid - properties can be selected for further analysis. Additionally, for each partner point the original complex is stored, which allows an easy evaluation whether this point is of interest for the user or not.
NAOMInova will soon be a part of the AMD tools software bundle. Our software is free for evaluation purposes and academic use.
 T. Inhester, et al. (2017). NAOMInova: Interactive Geometric Analysis of User-defined Substructures in Proteins. in preparation.
 E. Nittinger, et al. (2017). A Large-Scale Analysis of Hydrogen Bond Interaction Patterns in Protein-Ligand Interfaces. J. Med. Chem. Under revision